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Two Cases of Fatal Zopiclone Overdose
Journal of Analytical Toxicology
Two cases of death due to the ingestion of zopiclone are presented. Quantitative determinations of zopiclone yielded 1.4-3.9 mg/L in the blood, 0.81 and 8.7 mg/kg in the liver, and 13.5 and 133 mg in the stomach contents. Drug concentrations were interpreted relative to the case findings, published data, and a limited evaluation of therapeutic concentrations found in two cases of therapeutic zopiclone use. Zopiclone was extracted from buffered blood or digested liver or both with n-butyldoi:10.1093/jat/20.2.131 pmid:8868406 fatcat:3g36vztpgzd57pqoavn7xr6g2a