Three New Orcinol-Conjugated Hydrolysable Tannins from the Leaves of Cleyera japonica

Myeong Hwan Oh, Kwan Hee Park, Manh Heun Kim, Han Hyuk Kim, So Ra Kim, Min Won Lee
2013 Chemical and pharmaceutical bulletin  
Three new orcinol (3-hydroxy-5-methylphenol)-conjugated hydrolysable tannins, together with two known compounds were isolated from the leaves of Cleyera japonica (CJ), and have been tentatively named cleyeratannin A (1), cleyeratannin B (2) and cleyeratannin C (3). The chemical structures of these compounds were elucidated using 1 dimensional (1D)/2D NMR and high resolution FAB-MS, and the absolute configuration was confirmed by circular dichroism (CD). To evaluate their anti-oxidative
more » ... s, 1,1-diphenyl-2-picrylhydrazyl (DPPH)/free radical scavenging activity and nitroblue tetrazolium (NBT)/superoxide anion scavenging activity were determined.
doi:10.1248/cpb.c12-00572 pmid:23449204 fatcat:qvnpvi2qd5ctlnmkmfyvfv7vve