A simple, selective, rapid, precise and economical reverse phase high pressure liquid chromatographic method has been developed for the estimation of Azelnidipine from pharmaceutical Tablet dosage form. The method was carried out on a C 18 (250 mm x 4.6 mm i.d., 5 µ) column with a mobile phase consisting of acetonitrile: 0.5% triethyl amine (adjusted to pH 3.5 using orthophosphoric acid) (70:30 v/v) at a flow rate of 1.0 ml/min. Detection was carried out at 254 nm. The retention time of

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... pine was 4.9 min. The developed method was validated in terms of accuracy, precision, linearity, limit of detection, limit of quantitation and solution stability. The proposed method can be used for the routine analysis.