Inter- and Intraobserver reproducibility of T2 relaxation times of the discus interpubicus: A feasibility study at 3 Tesla

Kai-Jonathan Maas, Maxim Avanesov, Azien Laqmani, Julius Weinrich, Markus Sauer, Michael G. Kaul, Gerhard Adam, Marc Regier, Cyrus Behzadi, Jan Fritz
2018 PLoS ONE  
Objective To quantify standard values of the discus interpubicus in healthy subjects and to determine reliability and repeatability using T2 relaxation time measurements at 3T. Methods 20 asymptomatic participants (10 male, 10 female; mean age: 27.3 years ±4.1, BMI: 22.2 ±1.8) underwent a 3T Magnetic Resonance Imaging (MRI) of the pelvic region in a supine position. We included sagittal and para-axial T2w sequences centred over the pubic symphysis in order to identify the complete discus
more » ... plete discus interpubicus. For quantitative analysis, a multi-echo Turbo Spin Echo (TSE) sequence (including 12 echo times between 6.4 and 76.8 ms) was acquired and analysed by using an in-house developed quantification plugin tool (qMapIt) extending ImageJ. Two readers in consensus defined three central slices of the pubic symphysis with the greatest length. For each slice, both readers separately placed three regions-of-interest (ROI) covering the whole discus interpubicus. Both readers repeated the ROI placements in identical fashion after a four-week interval on the original MRI images. Statistical analysis included intraclass correlation coefficient (ICC), nonparametric Wilcoxon test, Fisher exact test and mean relaxation time in ms and 95% confidence intervals. OPEN ACCESS Citation : Maas K-J, Avanesov M, Laqmani A, Weinrich J, Sauer M, Kaul MG, et al. (2018) Interand Intraobserver reproducibility of T2 relaxation times of the discus interpubicus: A feasibility study at 3 Tesla. PLoS ONE 13(8): e0202698. https://doi. Conclusion T2 mapping of the discus interpubicus demonstrates good inter-and intrarater repeatability as well as reliability. Mean relaxation times were calculated with 48.6ms in healthy volunteers.
doi:10.1371/journal.pone.0202698 pmid:30133521 fatcat:kysgx7j6qvcclccl7y2lugq2gu