A Charge Transfer Determination of Paracetamol with Picric Acid

Nwanisobi Gloria
2018 Archives of Pharmacy & Pharmacology Research  
A cost effective and sensitive spectrophotometric method has been developed for the assay of paracetamol in pure and commercial forms. The method employed was charge transfer complexation. Paracetamol formed a 1:2 stoichiometric ratio with picric acid. The complex was quantified at 500nm. Beer -Lambert's law was obeyed within a concentration range of 5-10µg/ml with molar absorptivity of 2.6 x10 4 Lmol -1 cm -1 . The method was used for the determination paracetamol in pure and commercial forms with percentage mean recovery of 95%.
doi:10.33552/appr.2018.01.000507 fatcat:deujw6sxpzh3hl5q3gh43qzjoq