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Therapeutic Perspectives on the Modulation of G-Protein Coupled Estrogen Receptor, GPER, Function
2020
Frontiers in Endocrinology
Estrogens exert their physiological and pathophysiological effects via cellular receptors, named ERα, ERβ, and G-protein coupled estrogen receptor (GPER). Estrogen-regulated physiology is tightly controlled by factors that regulate estrogen bioavailability and receptor sensitivity, while disruption of these control mechanisms can result in loss of reproductive function, cancer, cardiovascular and neurodegenerative disease, obesity, insulin resistance, endometriosis, and systemic lupus
doi:10.3389/fendo.2020.591217
pmid:33329395
pmcid:PMC7719807
fatcat:yxjkbao6t5hbvf33qqffr437ea