Dr. Abdul Salam Memon, Dr. Shahida Khatoon, Dr. Riaz Ahmed Memon, Dr. Afzal Junejo
2015 The Professional Medical Journal  
Subjects and Methods: Subjects with clinical suspicion of acute appendicitis were selected according inclusion and exclusion criteria. A sample of 49 acute appendicitis patients and 37 controls were studied. The Blood samples were collected in sodium citrate vacutainers and processed on Sysmex KX 21 analyzers. The main analysis was the comparison of the difference of MPV between acute appendicitis and controls. Data was analyzed on SPSS version 21.0 by student's t-test, Chi-square test and
more » ... quare test and Pearson's correlation (r) was used to evaluate association of MPV with platelet counts and leukocytes. A p-value of ≤0.05 was taken significant. Results: The mean platelet volume and leukocytes were significantly elevated in patients with acute appendicitis. MPV and leukocytosis in controls and cases were noted as 7.93±2.1 vs. 9.10±2.9fl (p=0.0001) and 6980±120 vs. 13980±340 µL -1 respectively. MPV was positively correlated with leukocytosis (r=0.419) (p=0.0001), while Platelets showed a negative correlation. Conclusion: Elevated MPV and leukocytosis are observed in acute appendicitis. MPV may be exploited for clinical diagnosis of acute appendicitis but in a proper clinical context along with leukocytosis.
doi:10.17957/tpmj/15.2827 fatcat:josmya6h4jbelpzvz72qq6nepy