The main objective of this paper is to develop a novel boundary element technique for describing the three-dimensional (3D) biothermomechanical behavior of anisotropic biological tissues. The governing equations are studied on the basis of the dual phase lag bioheat transfer and Biot's theory for one-and two-temperature models. Because of the benefits of CQBEM, such as not being restricted by the complex shape of biological tissues and not requiring discretization of the interior of the treated

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... region, it can cope with complex bioheat models and has low use of RAM and CPU. CQBEM is therefore a flexible and efficient tool for modeling the distribution of bioheat in anisotropic biological tissues and associated deformation. The resulting linear equations arising from CQBEM are solved by the generalized modified shift-splitting (GMSS) iterative method which reduces the number of iterations and the total time of the CPU. Numerical findings show the validity, efficacy and consistency of the proposed technique.