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The crossbred gilts studied were aged 80 days (prepubertal), 180 days (prepubertal or postpubertal) and 260 days (postpubertal or pregnant). Estimates of metabolic clearance rate (MCR) of oestradiol and progesterone were consistently less (21 and 27%) in plasma than in blood, and these differences were not influenced by age of gilt. The MCR (1/day per kg body weight) for oestradiol and progesterone in plasma was greater (P < 0\m=.\05) for 80-day-old prepubertal gilts than for older gilts. Thedoi:10.1530/jrf.0.0750247 pmid:4032373 fatcat:wbqhhnzg7rd7lppi2ntoz7rtpq