CRP is one of the reliable diagnostics marker used in diagnosis of Neonatal Sepsis that has been widely available, most studied and preferred over the newly emerging infection markers. In this study, we have studies that even CRP assay has proven to be less time consuming and effective analyzing samples of neonates who are already on antibiotics treatment. In our study 40 neonates were proved to have neonatal sepsis which was based on signs and symptoms shown by patient. The other studies have

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... evealed, CRP biochemistry assay have high sensitivity and specificity as compare to HSS for diagnosis of NS; we also got 100% sensitivity and specificity for CRP testing. Hence we concluded that CRP is a good diagnostic marker for the infection in neonates at the time of initial assessment. In our study we used quantitative assay for CRP estimation which less time consuming and effective in analyzing samples of neonates who are already on antibiotics treatment.