Comprehensive Ex Vivo Transposon Mutagenesis Identifies Genes That Promote Growth Factor Independence and Leukemogenesis

Y. Guo, B. L. Updegraff, S. Park, D. Durakoglugil, V. H. Cruz, S. Maddux, T. H. Hwang, K. A. O'Donnell
2015 Cancer Research  
This study presents a broadly applicable approach for identifying and classifying functionally relevant genes in hematopoietic malignancies and offers new insights into the drivers of leukemogenesis.
doi:10.1158/0008-5472.can-15-1697 pmid:26676752 fatcat:2yv5ah5gwvai3hixwaxdijz54a