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Information technology plays an important role in medicine because of the advanced decision support systems (DSS) it can provide. We provide an overview of the building blocks necessary for a medical decision support system and introduce seven research articles in this special issue that describe the development and evaluation of individual medical DSS building blocks or complete medical DSS.doi:10.1016/j.dss.2006.02.001 fatcat:o6mqpgbu5faipenuyj3b3wnzri