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G protein-coupled receptors: abnormalities in signal transmission, disease states and pharmacotherapy
Acta Poloniae Pharmaceutica - Drug Research
The aim of this review is to present the research results and draw new conclusions about the impact of alterations in the signal transmission through the G protein-coupled receptors (GPCRs) on the formation of diseases and drug therapy. GPCR family is the largest and the most diverse group of membrane receptors. They transmit signals into the cell by interaction with different ligands, which include, inter alia, hormones, neurotransmitters, and photons. GPCRs are responsible for the proper
pmid:25272642
fatcat:koqfugbjejdufe34nenq7md64u