Successful Treatment of a Patient with Primary Sjögren's Syndrome Complicated with Pericarditis during Pregnancy

Kazuo Mutsukura, Hideki Nakamura, Nozomi Iwanaga, Hiroaki Ida, Atsushi Kawakami, Tomoki Origuchi, Masako Furuyama, Katsumi Eguchi
2007 Internal medicine (Tokyo. 1992)  
A 35-year-old woman with primary Sjögren's syndrome (pSS) developed fever and chest pain during pregnancy. When the dose of prednisolone was reduced, she experienced chest pain with elevated CRP and Ddimer, resulting in admission to our hospital with marked cardiomegaly and pleural effusion. Because there was no evidence of other autoimmune disorders or infection, oral prednisolone was increased to 30 mg daily with heparin, and hypercoagulopathy was carefully monitored. The patient's condition
more » ... atient's condition improved rapidly, and she delivered a healthy baby. This is the first case to support the beneficial effect of prednisolone in pericarditis with pSS, and illustrates its safety during pregnancy.
doi:10.2169/internalmedicine.46.0062 pmid:17634717 fatcat:hnchgvelozfzlfh4vutkhwykle