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A Reappraisal of the Histopathologic Criteria for the Diagnosis of Cutaneous Allogeneic Acute Graft-vs-Host Disease
American Journal of Clinical Pathology
A b s t r a c t To détermine the validity ofthe Lerner grading system and review the histopathologic findings of cutaneous acute graft-vs-host disease (aGVHD), 78 skin biopsy spécimens from 49 bone marrow transplant récipients were evaluated. Histopathologic sections were independently reviewed twice by 3 pathologists and classified (Lerner system), without knowledge of the patients ' clinical évolution. Intraobserver agreement in grading aGVHD was substantial to almost perfect. Interobserverdoi:10.1093/ajcp/112.6.791 fatcat:y55br5yonbd2dfm5wx5ae3uf5i