Fifteen cultivars of sweet potato (Ipomoea batatas L.) were harvested from the field of (All India Coordinated Research Project on Tuber Crops) AICRP, Horticulture Research Station, Mandouri and the analysis of biochemical composition was carried out to determine the best nutritive cultivars. It was carried out in the Post graduate lab, Department of Post Harvest Technology, Faculty of Horticulture, Bidhan Chandra Krishi Viswavidyalaya, Mohanpur, Nadia West Bengal, during the period from

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... period from 2017-2019. It was found that the tuber weight was varied significantly from 48.11gm to 540.45 gm among the different cultivars. The tuber length was recorded high in TSP-16-2 (12.22cm) and short in cultivar BCSP-10 (6.75cm).Maximum TSS value recorded in KISHAN (10.2°Brix) and the lowest value was recorded cultivar TSP-12-10 (8°Brix). Dry matter content was found higher in the cultivars TSP-12-6 (30.54%). Minimum content of dry matter was found in TSP-12-9 (23.55%). The highest total sugar value was found in the cultivars TSP-16-5 (2.55%). The cultivar with lowest total sugar content was found in TSP-16-8 (1.94%). The result indicated that the cultivars differed considerably in reducing sugars content. In the experiment highest content was found to be in the cultivar BCSP-10(1.21%). Lowest was found in the cultivars TSP-12-10 (0.83%).The highest Titratable acidity value was found in the cultivars KISHAN (0.416%) and Lowest was found in the cultivars TSP-12-10 (0.128%).