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New scintillation and semiconductor crystal detector design concepts, high density readout electronics, signal processing algorithms, and high performance computing technologies show promise to facilitate earlier detection of molecular-based disease. ABSTRACT | Positron emission tomography (PET) is used in the clinic and in vivo small animal research to study certain molecular processes associated with diseases such as cancer, heart disease, and neurological disorders and guide the discovery and development of new treatments. New PETdoi:10.1109/jproc.2007.913504 fatcat:y3foc3nfsneevdk2ki3ggbsozi