Identifying biomarkers as diagnostic tools in kidney transplantation

Valeria R Mas, Thomas F Mueller, Kellie J Archer, Daniel G Maluf
2011 Expert Review of Molecular Diagnostics  
There is a critical need for biomarkers for early diagnosis, treatment response, and surrogate end point and outcome prediction in organ transplantation, leading to a tailored and individualized treatment. Genomic and proteomic platforms have provided multiple promising new biomarkers during the last few years. However, there is still no routine application of any of these markers in clinical transplantation. This article will discuss the existing gap between biomarker discovery and clinical
more » ... lication in the kidney transplant setting. Approaches to implementing biomarker monitoring into clinical practice will also be discussed.
doi:10.1586/erm.10.119 pmid:21405969 pmcid:PMC3116652 fatcat:rivexgj3ojhxdakcaj7wyeuda4