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TNF-α (Tumor Necrosis Factor Alpha) and iNOS (Inducible Nitric Oxide Synthase) Expression in Rat Brain Infected by Mycobacterium tuberculosis Strain H37RV
2017
Journal of Tuberculosis Research
Tuberculosis is an infectious disease caused by the Mycobacterium tuberculosis. Mycobacterium tuberculosis will form the primary focus or Ghon focus in the lungs of infected people. The primary focus can break and get into the bloodstream and/or lymph to the entire body, including the central nervous system, especially the brain. Tuberculosis infection in the brain can cause microglia secrete inflammatory factors such as TNF-α and IL-1β is emerging as the body's immune response. The factors
doi:10.4236/jtr.2017.51006
fatcat:s4e62nyk75cevfd3vgrrmj6hcy