Use of the Urinary Protein/Urinary Creatinine Index in Patients with Preeclampsia

Javier Edmundo Herrera Villalobos, Ricardo García-Santana, Freddy Mendoza-Hernández, Paloma, Adriana Sil-Jaimes, Miguel Ángel Nares-Torices, Enrique Monares-Zepeda, Mirian Ovando-Aldana
2017 Obstetrics and Gynaecology Insights  
Preeclampsia is the main cause of maternal morbidity and mortality in Mexico, accounting for up to 34% of all maternal deaths. Current evidence refers to the usefulness of the protein/creatinine ratio as a predictor of preeclampsia, and its outcome is comparable with the determination of 24-hour proteinuria. To determine the usefulness of the protein/creatinine index in an isolated urine sample in patients with preeclampsia. A series of cases of pregnant women diagnosed with preeclampsia was
more » ... loyed in which the protein/creatinine index was calculated in an isolated sample of urine in order to describe the results, associating this index with the evolution of the patients in terms of maternal outcomes. Statistical analysis was performed in the SPSS ver. 20 statistical software program, evaluating the correlation between urinary protein/urinary creatinine ratio and the 24-h determination of urinary proteins, performing the Pearson correlation coefficient, with the determination of significant proteinuria >300 mg/dL in 24-h urine as gold standard. A protein/creatinine ratio equal to or greater than 0.3 mg/dL, obtained from an isolated urine sample, was considered as a proteinuria equal to or greater than ≥300 mg/dL in the analysis of 24-h urine. The protein/creatinine ratio could be used for rapid and reliable protein detection in patients with apresumptive diagnosis of preeclampsia.
doi:10.28967/ogi.2017.01.17002 fatcat:4kqtqs7mmfaltmjhiv73crtpoy