Cyanopeptoline CB071: A Cyclic Depsipeptide Isolated from the Freshwater Cyanobacterium Aphanocapsa sp

Hyukjae Choi, Sun Kwan Oh, Wonho Yih, Jungwook Chin, Heonjoong Kang, Jung-Rae Rho
2008 Chemical and pharmaceutical bulletin  
Cyanopeptolin CB071 (1), a trypsin inhibitor, was isolated from the freshwater cyanobacterium Aphanocapsa sp. Its complete structure was determined by detailed NMR spectroscopy and MS analyses, along with chemical reactions. The compound showed inhibition of trypsin at a concentration of IC 50 ‫5.2؍‬ m mM.
doi:10.1248/cpb.56.1191 pmid:18670126 fatcat:s6bjkvn7vvh3paw27c6holltui