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In vivo anti-hyperuricemic activity of sesquiterpene lactones from Lychnophora species
2019
Revista Brasileira de Farmacognosia
Hyperuricemia is the main cause of gout, an inflammation induced by uric acid deposition in joints. Drugs available present side effects, so there is a need for new treatment alternatives. Lychnophora species are used in folk medicine to treat inflammation, rheumatism and muscle pain. Goyazensolide (10 mg/kg), eremantholide C (25 mg/kg) and lychnopholide (25 mg/kg), sesquiterpene lactones isolated from Lychnophora species were previously studied and showed anti-hyperuricemic effects in mice.
doi:10.1016/j.bjp.2018.12.008
fatcat:hi27jyvn7na2fdgmyqunfrub6q