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Effect of Tumor Necrosis Factor-?? Gene Polymorphism on Peri-Implant Bone Loss Following Prosthetic Reconstruction
Purpose: The present study investigates the association between a specific polymorphism in the tumor necrosis factor (TNF)-␣ gene, consisting of allele 2 of TNF-␣ Ϫ308 , and periimplant bone loss following prosthetic reconstruction. Materials and Methods: This case-control study included 36 patients (20 women, 16 men; mean age 46 years) who had used implant-supported prostheses for a minimum of 6 months and a maximum of 31 months. The patients were nonsmoking, white Caucasian Brazilians, indoi:10.1097/id.0b013e31803277c1 pmid:17356374 fatcat:cg2dd2sftnfsxhm4a5z4t6rlyi