Original Article Effects of a carbohydrate loading on gastric emptying and fasting discomfort: an ultrasonography study

Wen-Ling Jian, Yan-Ling Zhang, Jun-Mei Xu, Shuang-Yin Xia, Hua Zeng, Ru-Ping Dai, Hui Li
2017 Int J Clin Exp Med   unpublished
Intake of clear liquids 2 h preoperatively is recommended by many anesthesiology societies. A novel carbohydrate-rich drink (CHO) has been developed for this purpose; however its effects on gastric empty and fasting discomfort have not yet been elucidated. The present study examined the effects of this CHO on gastric emptying and fasting discomfort in healthy volunteers. Methods: Thirty healthy volunteers received 400 mL CHO or 10% glucose solution after fasting overnight for at least 8 hours.
more » ... at least 8 hours. Each participant randomly ingested one drink and one week later took the other drink. Gastric emptying was examined via ultrasonography of cross-sectional areas (CSA) of the gastric antrum. The degrees of hunger, thirst, and mouth dryness were recorded over 180 minutes shortly before and after fluid intake. Results: Gastric CSA immediately increased after the ingestion of the CHO or glucose solution and returned to baseline by 60 min after ingestion (P > 0.05 vs 0 min). There were no differences in gastric CSA when comparing intake of the CHO and glucose solutions. Thirst and hunger were relieved at the time points measured after ingestion of both solutions vs before ingestion (P < 0.01). However, mouth dryness was still relieved 180 minutes after intake of the CHO, whereas the glucose solution had no such effect. Conclusion: Rapid gastric emptying and relief of fasting discomfort occurred with intake of both the glucose and the new CHO solutions. Thus, intake of the new CHO solution 2 hours preoperatively appears to be safe prior to anesthesia.