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Poliomyelitis was considered historically to be a major infectious disease of humans. Over the past few decades the implementation of widespread, effective vaccination programs in most countries has reduced the global burden of this potentially fatal and often severely debilitating viral disease to a minimally low level. However, polio-endemic regions remain in Afghanistan, Pakistan and Nigeria, where polio eradication has never eventuated. These isolated pockets pose a serious threat of thedoi:10.15344/2456-4028/2017/125 fatcat:cyejsb7hn5ef7g6rush25sqa4u