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Efficacy and Toxicity of Concurrent Chemoradiotherapy with Nedaplatin and S-1 for Head and Neck Cancer
Japanese Journal of Clinical Oncology
Objective: We investigated the efficacy and toxicity of concurrent chemoradiotherapy with nedaplatin and S-1 for head and neck cancer, as an alternative to cisplatin and 5-fluorouracil. Methods: A total of 31 patients were enrolled in this study. S-1 was administered orally twice a day for 14 days followed by a 2-week rest. Nedaplatin was intravenously administered on day 4. If possible, two courses of chemotherapy were performed. The radiotherapy was started concurrently with thedoi:10.1093/jjco/hyq196 pmid:21109512 fatcat:bqd3qtjzcrdq5eibby7dnup5vq