A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.
The file type is application/pdf
.
QSAR Modeling: Where Have You Been? Where Are You Going To?
2014
Journal of Medicinal Chemistry
Quantitative Structure-Activity Relationship modeling is one of the major computational tools employed in medicinal chemistry. However, throughout its entire history it has drawn both praise and criticism concerning its reliability, limitations, successes, and failures. In this paper, we discuss: (i) the development and evolution of QSAR; (ii) the current trends, unsolved problems, and pressing challenges; and (iii) several novel and emerging applications of QSAR modeling. Throughout this
doi:10.1021/jm4004285
pmid:24351051
pmcid:PMC4074254
fatcat:bzjqonekb5gkhojb2wpcvyn2l4