A Long Interval from a Spinal Cord Lesion to a Subsequent Brain Lesion in Primary Central Nervous System Vasculitis

Tomoya Kon, Yukihisa Funamizu, Chieko Suzuki, Tsugumi Sato, Hidekachi Kurotaki, Aiichiro Kurihara, Akira Kurose, Koichi Wakabayashi, Masahiko Tomiyama
2019 Internal medicine (Tokyo. 1992)  
Primary central nervous system vasculitis (PCNSV) is an uncommon vasculitis restricted to the small-and medium-sized vessels in the brain and spinal cord. Previously, only 9 cases have been reported that initially manifested as an isolated spinal cord lesion with subsequent brain involvement, where the longest interval from the onset to brain involvement was 1 year and 11 months. We herein report the case of an isolated spinal cord lesion with subsequent brain involvement appearing seven years
more » ... nd five months later. This case shows that brain lesions can develop after an extended interval from spinal onset in PCNSV.
doi:10.2169/internalmedicine.1667-18 fatcat:wlodxa7ycbevngdvvkavvesiny