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A NEW DELIVERY SYSTEM FOR DDAVP: CLINICAL EXPERIENCE OF DDAVP SPRAY PUMP IN MILD HAEMOPHILIA A AND vWD TYPE I
Until recently, the reliability and predectibility of the intranasal route of administration of DDAVP has been too poor to recommend it in routine practice.With the development of a new delivery system in the form of a spray puip we have previously shown that absorption and biological effect of DDAVP in volunteers is enhanced(1).In this patient study we conpared intranasal administration of 300 pg DDAVP using a newly developed pre-corrpression spray pinp with intravenous administration of 0.3 -doi:10.1055/s-0038-1644704 fatcat:hjpxf5bblzcbbgumtelvb4hvky