Correlation of Salivary Glucose level with Blood Glucose Level in Patients with Diabetes Mellitus

Gnanamoorthy Kothai, Acksa Alex, Aruna Bholenath Patil, Athanallur Raman Malathy, Prasanna Karthik Suthakaran
2020 International Journal of Research in Pharmaceutical Sciences  
Diabetes Mellitus (DM) is a systemic disorder characterized by hyperglycemia either due to insulin resistance or insulin deficiency. This can lead to many serious life-threatening complications if not managed properly by regular monitoring of glycemic status. Prevalence of fear of needles in the society make people non-compliant to regular monitoring. Thus, there is a need for a non-invasive method for determining the glycemic status of the individual. Salivary Glucose has the potential to be
more » ... e such tool. This study aimed to find whether a correlation between fasting blood glucose levels and fasting salivary glucose levels could be established in diabetic and non-diabetic individuals. 50 patients with DM and 50 patients without DM were studied. 5 ml of venous blood and 5 ml of unstimulated saliva after overnight fasting were collected from each participant and processed using standardized enzymatic methods. The data was analyzed using SPSS software. There was a strong and very significant positive correlation (r=0.800, p=0.001) between fasting salivary glucose levels and fasting blood glucose levels in patients with DM whereas the correlation was weak and insignificant in patients without DM (r=0.111, p=0.441). The cut off value for diagnosing DM was found to be ˃ 2.2mg/dl with 100% specificity and 100% sensitivity.
doi:10.26452/ijrps.v11ispl4.4314 fatcat:pvv2fb7csrgtnfguhyryoi4eoq