Microwave Irradiation Synthesis of Various Substituted Chalcones Using Various Heterogeneous Catalysts under Solvent - Free Conditions and their Biological Studies

SHWETA SHOREY, PRAKASH C. CHOUDHARY, KUMUD INTODIA
2013 Chemical Science Transactions  
Synthesis of eight substituted chalcones using various heterogeneous catalysts such as Mont-K10, anhydrous K 2 CO 3 , anhydrous ZnCl 2 and fused Ba(OH) 2 under MWI was carried out to improved Claisen -Schmidt condensation reaction. A comparative aspect of different compounds in respect of different catalysts, time taken and per cent yield has been discussed. The advantages of this process is to design and develop new synthetic routes to various bioactive chalcone which is environmentally
more » ... ironmentally desirable and economically viable. The structures of all the compounds have been established by analytical and spectral (IR, 1 H NMR, & mass) data. The synthesized compounds were also used for various biological screening.
doi:10.7598/cst2013.319 fatcat:p4wlccikzfg35a23t6ctfjh7se