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Pathophysiology of chemokines and chemokine receptors in dermatological science: A focus on psoriasis and cutaneous T-cell lymphoma
Zhōnghuá Pífūkē Yīxué Zázhì
Skin is an immunological organ with a delicate immunological network that governs the homeostasis and homing of the pro-and anti-inflammatory immune cells. Dysregulated immune response may result in psoriasis, a common inflammatory skin disease. Inappropriate immune surveillance, on the other hand, may cause the development of cutaneous lymphomas. Such homing of the immune cells likely depends on the interactions of chemokine and its receptors. Chemokine receptors and their correspondingdoi:10.1016/j.dsi.2012.08.004 fatcat:ewb553h3pna4zctog55xznmk6y