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Comparison of Methods for Combining Case-Control and Family-Based Association Studies
2009
Human Heredity
ples. Adding parental information to the CC part of the joint likelihood increased the power of generalised lo gistic regression under the TDTC but not the TDTCC scenario. Formal testing of differences between risk parameters in subsamples was the most sensitive approach to avoid confounding in combined analysis. Non-parametric analysis based on Monte-Carlo testing showed the highest power for ASPFCC samples. Abstract Objectives: Combining the analysis of family-based samples with unrelated
doi:10.1159/000212503
pmid:19365137
fatcat:a346muczszdq7grvorm7ewomju