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Physalis angulata is a medicinal plant used for the treatment of malaria, ulcer, pains and other diverse ailments. The present study evaluated the analgesic and anti-inflammatory activity of methanolic leaf extract of the plant. Acetic acid-induced abdominal contraction or writhing analgesic models in Swiss albino mice (13-23g) were used for studying analgesic activity of the leaf extract. 200, 300 and 400 mg/kg body weight of the extract were administered intraperitoneally. Analgesicfatcat:zaiskufkebg2pnbc7t7az3deki