Serum Amyloid A and Haptoglobin Levels in Bovine Amyloidosis

Eiji TAKAHASHI, Yuuji UZUKA, Sigeyuki TANABE, Motoyoshi SATOH, Hidefumi FURUOKA
2007 Journal of Veterinary Medical Science  
Serum amyloid A (SAA) and haptoglobin (Hp) levels were determined in 25 cows suffering from amyloidosis. SAA levels in cows with amyloidosis ranged between < 0.3 and 225.8 µg/ml, with a median level of 105.1 µg/ml, and Hp levels ranged between < 20 and 1860 µg/ml, with a median level of 950 µg/ml. These levels were significantly higher than the levels observed in healthy cows (SAA levels ranged from < 0.3 to 13.5 µg/ml, with median of 1.4 µg/ml, and Hp levels were undetectable in all cases),
more » ... e in all cases), but were not significantly different from the levels observed in control cows with chronic inflammation. There was a significant correlation between SAA and Hp levels in cows with chronic inflammation , but not in cows with amyloidosis. It was concluded that the serum SAA levels in cows with amyloidosis might be changed by some factor other than inflammation. KEY WORDS: amyloidosis, haptoglobin, serum amyloid A.
doi:10.1292/jvms.69.321 pmid:17409654 fatcat:lzfu3rpmdfg7plni2vcpdlhlty