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This Study aimed to investigate the effect of garlic extract against multidrug resistance ofStaphylococcus aureus and E. coli isolated from urine. Isolates were identified by usingbiochemical tests. The susceptibility of these microorganisms towards the most effectiveantibiotics were studied by using disc diffusion method. The multidrug resistancemicroorganisms were challenged with garlic extract using serial dilutions and the technology ofELISA spectrophotometer. The results of this studydoi:10.24126/jobrc.2015.9.1.407 fatcat:ix7tgffifvdmvpjhcuqkbkhpga