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OSW-1 is a natural saponin and its anticancer activities are 10-to 100-fold more potent than many well-known anticancer agents in clinical use. Its cytotoxicity profile suggests that it may have a unique mode of action different from other well-known anticancer agents. However, its mechanism still remains a mystery after years of study, and no paper has ever been published in this area. Extensive in vitro and in vivo testing has been conducted and toxicological experiments have also beendoi:10.17077/etd.tau7hfml fatcat:6oe4n4uapfbxvdkoeqrw2hh4vu