Huge Pancreatic Acinar Cell Carcinoma with High Levels of AFP and Fucosylated AFP (AFP-L3)

Atsushi Hiraoka, Hiromasa Nakahara, Hideki Kawasaki, Yuko Shimizu, Satoshi Hidaka, Yusuke Imai, Hiroki Utsunomiya, Haruka Tatsukawa, Nayu Tazuya, Hiroka Yamago, Nobukazu Yorimitsu, Tetsuya Tanihira (+8 others)
2012 Internal medicine (Tokyo. 1992)  
A 25-year-old Japanese woman with a large abdominal tumor (10 cm in diameter) and high level of serum alpha-fetoprotein (AFP, 1,222.4 ng/mL) was introduced and admitted to our hospital in January 2011. Preoperative imaging modalities could not identify the tumor origin. There was no chronic hepatic viral disease, however, the elevated level of fucosylated AFP (87.8%) and connection with the left hepatic lobe led us to diagnose the tumor as a hepatocellular carcinoma. Surgical resection was
more » ... resection was performed in February. Histological findings revealed a pancreatic acinar cell carcinoma (ACC). Herein, we provide details of this difficulty to diagnose a case of ACC.
doi:10.2169/internalmedicine.51.6536 pmid:22687839 fatcat:hprgfn6dqzd5bmbkswyivpvgre