A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2018; you can also visit the original URL.
The file type is
The Liver-Enriched Transcription Factors HNF-1α, HNF-3β, and C/ EBPβ Contribute to the Growth Hormone-Induced Transcription of the Progranulin a Gene in Zebrafish (Danio Rerio)
Journal of Aquaculture Research & Development
Progranulin (PGRN) is a secreted growth factor that has been implicated in diverse biological processes including wound healing, embryo development, morphogenesis and disease. We previously showed that PGRN is induced along with IGF-1 in tilapia liver upon GH administration. In the present study, we demonstrate that the coinduction of PGRN and IGF-1 by GH administration is a common regulation in fish also presented in zebrafish. To understand the regulatory mechanism of GH-induced PGRNdoi:10.4172/2155-9546.1000237 fatcat:yksjeu6rarbkdn4yuatre6jc7u