Oxidative stress in animals: role in oncogenesis from pathomorphologist view
Оксидативный стресс у животных: роль в онкогенезе глазами патоморфолога

Natal'ya Mitrohina
2020 Russian veterinary journal  
Oxidative stress is a pathological accumulation of free radicals that contribute to the launch of intracellular damaging action mechanisms. Free radical is an atom possessing free or missing electron, and seeking to restore the lost electron, taking it from other molecules ― as a result a new free radical is formed. The mechanism is chain reaction-based. Hypoxia acts as an additional stimulus to the appearance of oxygen free radicals. Cell hypoxia develops following any type of cell damage:
more » ... of cell damage: mechanical, bacteriological, chemical, etc. Cell hypoxia inevitably leads to the development of an inflammatory reaction, which is followed by the formation of oxygen free radicals and, as a result, by oxidative stress development.
doi:10.32416/2500-4379-2020-5-27-30 fatcat:a345r3syl5b4hkhk2qalyfbt2m