THU0262 Changes in sonoelastographic characteristics in sjÖgren's syndrome – a five-year follow up

B Hofauer, M Bas, N Mansour, A Knopf
2017 Poster Presentations   unpublished
9), Sjögren Syndrome (5) and mixed connective tissue disease (5). The allO group included rheumatoid arthritis (28), psoriatic arthritis (10), spondyloarthritis (11), and JIA (8). The proportion of children born at term was lowest in patients with SLE (79%), compared to OCTD (91%) and allO patients (88%). The table shows selected baseline and outcome parameters. In early pregnancy, more patients with SLE reported low disease activity and a higher proportion was diagnosed by the rheumatologist
more » ... having mild disease than in the other diagnoses groups. During pregnancy, flares occurred rarely in SLE and OCTD patients, whereas a substantial proportion of patients in the allO group had multiple flares. However, serious complications during and after pregnancy occurred more often in SLE and OCTD patients, as well as congenital anomalies and complications. Due to the low number of events and completed pregnancies, associations to suspected risk factors couldn't be analyzed yet. Conclusions: Although most patients with SLE or OCTD had a favorable course and outcome of pregnancy, compared to patients with other inflammatory rheumatic diseases substantially more complications and adverse pregnancy outcomes occurred. The association to specific risk factors predicting adverse pregnancy outcomes could not yet be analyzed. At the time of the EULAR congress we expect at least twice as much completed pregnancies. All patients with SLE and OCTD should be tightly screened during pregnancy with timely and adequate adjustment of drug treatments. Acknowledgements: Rhekiss is a collaborative project of the DRFZ Berlin and the Rheumazentrum Rhein-Ruhr e.V. Düsseldorf, jointly funded by both institutions.
doi:10.1136/annrheumdis-2017-eular.6436 fatcat:hhzksvmwlvatxhzpqc4f6dfmke