Acetylcholinesterase Inhibitory Effect and Characterization of the Essential Oil of Plectranthus aegyptiacus (Forssk.) C. Chr. Growing in Nigeria

Christianah Abimbola Elusiyan, Idowu Olawuni, Tiwalade Adewale Olugbade, Omolara Orafidiya, Armando McDonald
2018 Medicinal & Aromatic Plants  
Essential oil of fresh leaves of Plectranthus aegyptiacus (Forssk.) C. Chr. collected in Nigeria was analyzed to determine its chemotype. A total of 30 compounds were identified. Constituents identified were mainly mono and sesquiterpenoids with the major components, accounting for about 76% of the components, being α-terpinene (6.9%), p-cymene (14.2%), γ-terpinene (5.5%), carvacrol (10.0%), α-copaene (5.3%), α-caryophyllene (5.8%), germacrene-D (11.6%), δ-cadinene (8.4%) and α-cadinol (8.4%).
more » ... he essential oil showed anticholinesterase inhibitory activity with an IC 50 of 8.29 ± 0.67 mg/ml.
doi:10.4172/2167-0412.1000316 fatcat:vyrzo3ayxfathpfa252e6ndaom