Pathogenesis of Hypertension -Kidney as a Pathogenetic Organ of Hypertension

2001 Internal medicine (Tokyo. 1992)  
netic and environmental factors and the trophic effect on vascular muscle may play roles in the long-term regulation of arterial pressure. The causes, however, of sympathetic activation and its precise mechanismscontributing to the pathogenesis of essential hypertension remain to be conclusively established. References 1) Folkow B. Physiological aspects of primary hypertension. Physiol Rev 62: 347-504, 1982. 2) Goldblatt H, Lynch J, Hanzal RF, et al. Studies on experimental hypertension.
more » ... ypertension. Production of persistent elevation of systolic blood pressure by means of renal ischemia. J Exp Med 59: 347-379, 1934. 3) Peet MM. Results of bilateral supradiaphragmatic splanchnicectomy for arterial hypertension. N Engl J Med 236: 270-277, 1943. 4) McCubbin JW, Green JH, Pae IH. Baroreceptor function in chronic renal hypertension. Circ Res 4: 205-210, 1956. 5) Cowley AWJr, Liard JF, Guyton AC. Role of the baroreceptor reflex in daily control of arterial blood pressure other variables in dogs. Circ Res
doi:10.2169/internalmedicine.40.153 fatcat:nomwxztn6rdz7dgizo5qps7vwa