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Objective: To conduct a literature review on the diagnosis and management of Paget's disease of bone. Materials and methods: This scientific statement was generated by a request from the Brazilian Medical Association (AMB) to the Brazilian Society of Endocrinology and Metabolism (SBEM) as part of its Clinical Practice Guidelines program. Articles were identified by searching in PubMed and Cochrane databases as well as abstracts presented at the Endocrine Society, Brazilian Society fordoi:10.1590/0004-2730000002941 pmid:25211441 fatcat:iudfyeqgjbgqnk6rhv5vtvrskm