ANATOMICAL VARIABILITY OF ORGANS VIA PRINCIPAL FACTOR ANALYSIS FROM THE CONSTRUCTION OF AN ABDOMINAL PROBABILISTIC ATLAS

Mauricio Reyes, Miguel A Gonzalez Ballester, Zhixi Li, Nina Kozic, See Chin, Ronald M Summers, Marius George Linguraru
2009 IEEE International Symposium on Biomedical Imaging  
Extensive recent work has taken place on the construction of probabilistic atlases of anatomical organ. We propose a probabilistic atlas of ten major abdominal organs which retains structural variability by using a size-preserving affine registration, and normalizes the physical organ locations to an anatomical landmark. Restricting the degrees of freedom in the transformation, the bias from the reference data is minimized, in terms of organ shape, size and position. Additionally, we present a
more » ... cheme for the study of anatomical variability within the abdomen, including the clusterization of the modes of variation. The analysis of deformation fields showed a strong correlation with anatomical landmarks and known mechanical deformations in the abdomen. The atlas and its dependencies represent a potentially important research tool for abdominal diagnosis, modeling and soft tissue interventions.
pmid:20628477 pmcid:PMC2902185 fatcat:zdemschvxbc75fxwgmm4j6puti