Natural Polyamines and Their Biological Consequence in Mammals

Jiří Patočka, Glenn D. Kuehn
2000 Acta Medica  
The polyamines (putrescine, cadaverine, agmatine, spermidine and spermine), wide-spread in all organisms, have been shown to play a role in regulation of growth and differentiation of virtually all types of cells. Their role in many physiological and pathophysiological processes have been studied very intensively during the last two decades. Inhibitors of polyamine biosynthesis have potential clinical uses as antitumor and antiparasitic agents. The brief summary with regard to their biological
more » ... o their biological consequences in mammals is discussed in this paper.
doi:10.14712/18059694.2019.124 fatcat:rynpto5fmnbdjikr2b3kez7j2u