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The Presence of AC133-Positive Cells Suggests a Possible Role of Endothelial Progenitor Cells in the Formation of Choroidal Neovascularization
Investigative Ophthalmology and Visual Science
PURPOSE. Recent evidence suggests that vasculogenesis as well as angiogenesis occurs throughout the body during neovascularization. The recruitment of circulating stem cells is a key feature of vasculogenesis. The purpose of the present study was to determine whether markers of endothelial progenitor cells (EPCs) are present in choroidal neovascularization (CNV) secondary to age-related macular degeneration (AMD). METHODS. Surgically excised CNV (n ϭ 9) membranes from patients with AMD weredoi:10.1167/iovs.05-0779 pmid:16565404 fatcat:cmeqmw5sabezrpv2vylukybnry