SPECIES DIVERSITY AMONG THE GENUS STREPTOMYCES MEMBERS ISOLATED FROM CLINICAL MATERIAL

A. V. Lyamin, V. S. Tereshchenko, A. V. Zhestkov, D. D. Ismatullin
2019 Infekciâ i Immunitet  
Аbstract. Recently, both in Russia and around the world, the number of cases detecting acid-fast microbial members from the order Actinomycetales while developing human bacterial infections has been increased. The most important are pathogens in this bacterial order are members from the families Mycobacteriaceae, Nocardiaceae, Gordoniaceae, Tsukamurellaceae, Promicromonosporaceae, Brevibacteriaceae, Streptomycetaceae. This work is devoted to analyze prevalence and species diversity of
more » ... tives of the family Streptomycetaceae from the genus Streptomyces, isolated from clinical material upon examining for tuberculosis. There were examined 865 cultures of clinical material samples while examining for tuberculosis, in which signs of growth of contaminating microflora were revealed, as well as 316 cultures of clinical material samples obtained during examination for tuberculosis, in which signs of growth of non-tuberculosis mycobacteria (NTM) were detected. The material was collected from January 2016 to January 2019. Samples with signs of growth of contaminating microflora allowed to identify 1,093 strains, from samples with signs of growth of NTM - 352 strains. Among them, the number of representatives of the genus Streptomyces comprised 39 strains. All streptomyces strains were isolated from sputum. Variety of isolated streptomyces: S.phaeochromogenes (13 strains), S.albus (1 strain), S.avidinii (1 strain), S.badius (2 strains), S.chartreusis (2 strains), S.griseus (1 strain ), S. hirsutus (2 strains), S. lavendulae (3 strains), S. violaceoruber (10 strains). Species identification was not possible for 4 strains. Analyzing the data obtained, it is possible to draw a conclusion about the moderate distribution of representatives of the genus Streptomyces in pattern of contaminating microflora while examining for tuberculosis. In pattern structure of isolated microorganisms, streptomyces accounted for 3.3%. Among the microflora isolated from culture with signs of NTM growth, streptomyces was presented by single [...]
doi:10.15789/2220-7619-sda-1838 doaj:de0f13ce4b45464eb68f49b263db0e14 fatcat:hvblfts7cvadnpxrka3xmhvovu