Environmental exposure to pesticides and respiratory health

Ali Mamane, Chantal Raherison, Jean-François Tessier, Isabelle Baldi, Ghislaine Bouvier
2015 European Respiratory Review  
Respiratory effects of environmental exposure to pesticides are debated. Here we aimed to review epidemiological studies published up until 2013, using the PubMed database. 20 studies dealing with respiratory health and non-occupational pesticide exposure were identified, 14 carried out on children and six on adults. In four out of nine studies in children with biological measurements, mothers' dichlorodiphenyldichloroethylene (DDE) blood levels during pregnancy were associated with asthma and
more » ... ed with asthma and wheezing in young children. An association was also found between permethrin in indoor air during pregnancy and wheezing in children. A significant association between asthma and DDE measured in children's blood (aged 7-10 years) was observed in one study. However, in three studies, no association was found between asthma or respiratory infections in children and pesticide levels in breast milk and/or infant blood. Lastly, in three out of four studies where post-natal pesticide exposure of children was assessed by parental questionnaire an association with respiratory symptoms was found. Results of the fewer studies on pesticide environmental exposure and respiratory health of adults were much less conclusive: indeed, the associations observed were weak and often not significant. In conclusion, further studies are needed to confirm whether there is a respiratory risk associated with environmental exposure to pesticides. @ERSpublications Occupational pesticide exposure increases respiratory health risk but data are unclear for environmental exposures
doi:10.1183/16000617.00006114 pmid:26324808 fatcat:rx2eu3vd5zemnoakzb7vp3y4ga