Hexokinase, differentiation and growth rates of transplanted rat tumors

W E Knox, S C Jamdar, P A Davis
1970 Cancer Research  
Concentrations of hexokinase in 18 types of transplanted rat tumors were significantly correlated with the measured growth rates and also paralleled the degrees of loss of histological differentiation of these tumors. The correlations confirm the similar relationship already found among hepatomas and extends it to some nonhepatic tumors of the rat. The normal tissues, fetal and regenerating liver, grew equally as fast as the fastest tumors but contained signifi cantly less hexokinase.
pmid:4318924 fatcat:o5yshyvyrbdpxfvotq4cbmfwcy